Hematology | Moving Toward Precision Medicine in Treating Newly Diagnosed Acute Myeloid Leukemia
AML is the most common acute leukemia in adults and is characterized by the clonal expansion of myeloblasts in the peripheral blood and bone marrow, resulting in ineffective hemtopoiesis and bone marrow failure. AML is a heterogeneous disease, with a plethora of genetic mutations and translocations that contribute to disease initiation and progression. The standard approach to therapy has been induction with cytarabine + anthracycline, followed by consolidation therapy. Recent advances have led to the development of novel, targeted agents and improved chemotherapy options, that have increased PFS and OS in patients with AML. These agents represent the first steps to individualizing patient care. Using patient cases, this activity reviews the pathophysiology and current state of management of AML, highlighting the optimal incorporation of targeted agents for newly-diagnosed, de novo AML and improved chemotherapeutic options for treatment-related AML.
Hematology Consults.com is a real-world focused, interactive, case-based, e-learning platform. Here, you will find interactive, written, enduring, Continuing Education (CE) modules accredited by the Institute for Johns Hopkins Nursing, developed and executed with clinical oversight by top experts in many hematology specialties. Activities are available on a wide range of topics, and allow participants the opportunity to apply the information learned in day-to-day patient care.
Ivana Gojo, MD
Associate Professor of Oncology
DJohns Hopkins School of Medicine
Co-Director, Leukemia Drug Development Program
Division of Hematologic Malignancies
Sidney Kimmel Comprehensive Cancer Center
- Accreditation Statement: The Institute for Johns Hopkins Nursing is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
- Statement of Contact Hours: This 0.5 contact hour educational activity is provided by The Institute for Johns Hopkins Nursing. The 0.5 contact hours will be awarded from the Hematology Consults website after the completion.
- Conflict of Interest: It is the policy of The Institute for Johns Hopkins Nursing to require our continuing nursing education program faculty and planning committee members to disclose any financial relationships with companies providing program funding or manufacturers of any commercial products discussed in the program. The planning committee and program faculty report that they do not have financial relationships with manufacturers of any commercial products they discuss in the program.
- Commercial Support: This educational activity has not received any form of commercial support.
- Non-Endorsement of Products: The Institute for Johns Hopkins Nursing and the American Nurses Credentialing Center does not endorse the use of any commercial products discussed or displayed in conjunction with this educational activity.
- 0.50 ANCC
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Click HERE to be directed to the Hematology Consults website. Select the desired article and proceed as instructed on the site. A certificate of participation will be available online immediately following successful completion of the activity.